PGD Treatment Centre

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PGD(Prenatal Genetic Diagnosis)

Prenatal genetic diagnosis is done by the best infertility specialist in Hyderabad, Dr. Rohini Devi in the Motherhood fertility centre, which is considered as the best fertility centre in Hyderabad and found that there are certain cytogenetic, molecular genetic, and molecular cytogenetic methods & advanced ultrasonography. In the fertility centres in Hyderabad, an increasing number of monogenic diseases can be diagnosed prenatally by doing either genetic testing or biochemical testing.  But Polygenic, as well as multifactorial diseases, can’t be diagnosed properly by genetic testing at the present stage, although multiple malformations can be ascertained prenatally by ultrasonography process. That’s why there are pgd treatment centres, where the pgd specialist in Hyderabad find out the actual reason of PGD.

The prenatal diagnosis of chromosomal abnormalities by karyotyping: INDICATIONS ARE-

Maternal age: Chromosomal anomalies increases with maternal age. Ex:Trisomy 21 (Down syndrome).

The following outcome is an abnormal result shown in non-invasive screening test by the best fertility doctors in Hyderabad or by a PCOS specialist in Hyderabad.

Following an ultrasound outcome which increases the possibility of a chromosomal problem.

the diagnosis is done In the presence of a known translocation, inversion or insertion in one of the parent.

A chromosomal anomaly test in an existing child. Ex: after the birth of a child with trisomy.

Genetically determined diseases can be divided into three groups:

Chromosomal abberations.

Monogenetic diseases.

Polygenetic/multifactorial diseases.

Genetic carrier screening:

This is a simple blood test to analyse your DNA to know whether it carries a gene for a particular disease and transfer of it to your child.

First trimester screening:

To all woman at 11 or 12 weeks of pregnancy done by ultrasound and blood test. With these we can know some genetic conditions, including Down syndrome.

Cell-free DNA screening:

Also known as noninvasive prenatal screening. To verify the chromosomal abnormalities, this blood test uses the fetal DNA circulating in the mother’s blood. It’s the most accurate screening test for detecting the risk of Down syndrome in the IVF hospital in Hyderabad.

Amniocentesis

Normally, Amniocentesis is done under ultrasonographic control, in between 15 to 17 weeks of pregnancy. Near about 15 mL of amniotic fluid would normally be aspirated. Chromosomal analysis requires prior to cell culture, after this metaphase chromosomes are analyzed numerically and structurally. To find out the levels of alpha fetoprotein (AFP), uncultured amniotic fluid can be used, which is present in great concentrations in an open neural tube defects and other disorders like abdominal wall defects (e.g., gastroschisis).

Chorionic villus sampling (CVS) and amniocentesis:

To collect a sample of fully fetal cells to test for chromosomal abnormalities, both the tests involve inserting a needle into your uterus. These tests can provide you the exact result if your baby has a particular condition, but both procedures carry small risk of miscarriage. All these tests are done during the pgd treatment in Hyderabad in the pgd treatment centres in Hyderabad.

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